YENİDOĞULANLARDA NEKROTİK ENTEROKOLİT ZAMANI BİOKİMYƏVİ MARKERLƏRİN PROQNOSTİK ƏHƏMİYYƏTİ

Nasirova S.R.; Mehdiyeva S.A.

doi:10.28942/jpp.v7i1.118

Vol. 7 No. 1 (2021)

Original articles

Prognostic value of biochemical markers during necrotizing enterocolitis in newborns

Published: January 11, 2022

DOI: https://doi.org/10.28942/jpp.v7i1.118

Abstract

During the study we examined the prognostic value of MMP-2, MMP-9, MMP-17, catelicide, transferrin and fecal calprotectin, which are biochemical markers in necrotizing enterocolitis in newborns. To achieve this goal, 110 sick newborns were observed. The newborns were divided into the following groups: Group I-49 patients with first stage of NEC, group II-48 patients with second stage of NEC, group III-13 patients with third stage of NEC. The control group consisted of 30 healthy newborns. The study used variational, discriminant, dispersive, and ROC- analysis. During the predictive evaluation in the study of matrix-metalloproteinase, which are molecular-biochemical markers, the total diagnostic weight of the test was for MMP-17 87.5%, for MMP – 9 85%, and for MMP-285%, which indicated the high predictive value of these markers.

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Prognostic value of biochemical markers during necrotizing enterocolitis in newborns

Abstract

References

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