Comparative analysis of efficiency of application respiratory and surfactant therapy with curosurf in preterm infants with respiratory distress syndrome

Abstract

The aim of the study was a comparative evaluation of the effectiveness and appropriateness of applying surfactant replacement therapy with Curosurf and noninvasive method of continuous posi-tive airway pressure (Continuous Positive Airways Pressure) (CPAP) in preterm infants with res-piratory distress syndrome (RDS). The complex, clinical, laboratory and instrumental examination of 363 premature newborns with RDS, with gestational age less than 34 weeks was performed.
It is revealed, that the positive variations of radiological parameters are marked during applica-tion of nasal СРАР and early introduction of Curosurf. Parameters of the oxygen status are impro-ved.
İmprovement and implementation of algorithm of intensive and intensive care, as well as early and late application of exogenous surfactant, will reduce the early neonatal mortality,assist success-ful nursing of premature newborns especially those with very low and extremely low birth weight.