The role of pap smear, HPV types and punch biopsy in evaluation of cervical pathologies
Abstract
Aim of study: Aim of our study is to determine the relation between high risk HPV(16,18,31,33) types, Pap smear and punch biopsy results. Material and methods: We used for our study patients which referred with abnormal cervical lesions and pathological cytology findings, from 2010-2017 years in Derince Training and Research Hospital. The data of the patients who underwent colposcopy were examined retrospectively. 151 patients were included in the study. Results: As a result of study-high risk lesions (CIN2-3) were observed in 18,18% (n=8/44) of NORMAL,10% (n=2/20) of ASCUS,27,27% (n=6/22) of LSIL,50% (n=5/10) of HSIL smear result reported patients. The result was reported as cervical squamous cell carcinoma in 1 patient with HSIL and 1 patient with LSIL. As a result, high–risk lesions (CIN2 and CIN3) were found 30,18% (n=16/53) in pathologic evaluation in HPV type 16 and 18 positive patients. In one patient with HPV18 was detected cervical squamous cell carcinoma. In our study was high risk lesions in 40% (4/10) of HPV other type patients. Pap smear result was reported as normal in 56,81% (n=25/44) of HPV type 16 and 18 patients,13,63% (n=6/44) of these patients were smear LSIL and HSIL.50% (n=3/6) of other positive HPV types Pap smear result reported as LSIL. Conclusions: Combined evaluation of Pap smear, colposcopy and punch biopsy while examining cervical pathologies is more convenient, than using these methods sepa-rately and more reliable approach to diagnosis of precancerous lesions.
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Declarations: Ethics approval and consent to participate. The study protocol was approved by the Ethics Committee of the Kocaeli University (registration number KU GOKAEK 2017/368). The patient gave her written consent. Competing interests. The author declares that he has no competing interests. Funding. The author declared that this study has received no financial support Conflict of interest. The author declares that there is no conflict of interest regarding the publication of this paper.
Keywords
мазка
Ударная биопсия
новообразования шейки матки Kolposkopiya
İnsan Papilloma Virusu
panksion biopsiyası
uterus servikal neoplazma Colposcopy
Pap smear
Punch biopsy
uterine cervical neoplasm’s