The aim of the research work was to study the predictor role of the PECAM, H4R and IgG1 allergomarkers in the formation of allergic pathologies in premature infants. The obtained results emphasize the need to determine immunological markers from the first days of life, along with the study of perinatal and neonatal risk factors in predicting atopic diseases. Being higher in children with a developing AtD in comparison with other groups of children, the level of each of these markers in the neonatal period is determined in relation to the statistically verified result of PECAM. The level of H4R is more informative with respect to the severity of AtD and is therefore recommended for use as a predictive marker of disease severity.
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