Using of erythropoietin as a preventive method for the treatment of anemia in premature infants.
Abstract
Based on the literature data and the results of our own research, the review provides information on the history of the study and modern use of recombinant human erythropoietin (rhEPO), its biological action, effectiveness for the prevention and treatment of early anemia of prematurity, as well as as a neuroprotector in newborns and children in the first months of life. born with very low and extremely low birth weight. In the long term, rhEPO improves cognitive function, motor, and language abilities in premature infants, and accelerates the recovery of neurological functions in children with very low birth weight. The presented data indicate that a more thorough study of the biological action of rhEPO can significantly expand the range of its application. According to the authors, the discussion continues about the positive impact of the use of rhEPO in early anemia of prematurity.
References
Проблемы трансфузий препаратов крови у недоношенных детей. Методическое пособие для врачей. Воронеж – 2017, 15с.
Aher S.M., Ohlsson A. Late erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants // Cochrane Database Syst. Rev. 2014. Vol. 4. CD004868.
New H.V., Berryman J., Bolton-Maggs H.B., Cantwell C. et al. Guidelines on transfusion for fetuses, neonates and older children // Br. J. Haematol. 2016. Vol. 175. P. 784-828
Von Lindern J.S., Lopriore E. Management and prevention of neonatal anemia: current evidence and guidelines // Expert Rev. Hematol. 2014. Vol. 2. P. 195-202
Шарафутдинова Д.Р., Балашова Е.Н., Ионо О.В. и др. Эффективность применения различных схем терапии рекомбинантным человеческим эритропоэтином у детей с очень низкой и экстремально низкой массой тела // Вопросы гематологии/онкологии и иммунопатологии в педиатрии, 2019; 18 (2): 75‒82).
Ohlsson A., Aher S.M. Early erythropoiesis-stimulating agents in preterm or low birth weight infants. Cochrane Database Syst Rev 2017; 16: 11
Becquet O., Guyot D., Kuo P., Pawlotsky F. et al. Respective effects of phlebotomy losses and erythropoietin treatment on the need for blood transfusion in very premature infants // BMC Pediatr. 2013. Vol. 13. P. 176
Белоусов Ю.Б., Омельяновский В.В., Белоусов Д.Ю. Четыре стратегии лечения анемий у онкологических больных в России. Качественная клиническая практика. 2008; 2: 71–8
Warwood TL, Lambert DK, Henry E, Christensen RD. Very low birth weight infants qualifying for a 'late' erythrocyte transfusion: does giving darbepoetin along with the transfusion counteract the transfusion's erythropoietic suppression? J Perinatol 2011; 31 (l1): 17–21
Egrie JC, Browne JK. Development and characterization of novel erythropoiesis stimulating protein (NESP). Nephrol Dial Transplant 2001; 16 (3): 3–13. DOI: 10.1093/ndt/16.suppl_3.3
Ohls RK, Kamath-Rayne BD, Christensen RD et al. Lowe Cognitive outcomes of preterm infants randomized to darbepoetin, erythropoietin, or placebo. Pediatrics 2014; 133 (6): 1023–30. DOI: 10.1542/peds.2013-4307
Watanabe D., Suzuma K., Matsui S. Erythropoietin as retinal angiogenic factor in proliferative diabetic retinopathy. N. Engl. J. Med. 2005;353:782–792. DOI: 10.1056/ NEJMoa041773
Chen Y., Connor K.M., Aderman C.M., Smith L.E. Erythropoietin deficiency decreases vascular stability in mice. J. Clin. Invest. 2008;118(2):526–533
Figueras-Alloy J., Alvarez-Dominques E., Morales-Ballus M., Salvia-Roiges M.D., Moretones-Sunol G. Early administration of Erythropoietin in the extreme premature, a risk factor for retinopathy of prematurity? Ann. Hediatr (Barc). 2010;73(6):327–333. DOI: 10.1016/ j. anpedi. 2010.09.001
Chou H.H., Chung M.Y., Zhou X.G., Lin H.C. Early Erythropoietin Administration does not Increase the Risk of Retinopathy in Preterm Infants. Pediatr Neonatol. 2017;58(1):48–56. DOI: 10.1016/j.pedneo.2016.03.006
Keywords
эритропоэтин
недоношенные дети vaxtından əvvəl doğulmuşlarda anemiya
eritropoetin
vaxtından əvvəl doğulanlar. anemia of prematurity
erythropoietin
preterm infants