The literature review shows the important role of the cytokine system in complex protective reactions inacute respiratory pathologies in children. It is known that IL-1β, IL-6, IL-18 were multifunctional pro-inflammatory cytokines that, playing an important role in the differentiation and activation of cells of the immune system, influenced immunopathogenesis, the clinical course of the disease, and the activity of the inflammatory process.The study of the features of the cytokine system allows us to predict the clinical course of acute respiratory infections in children, to improve therapeutic and preventive measures
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