Significance of oxygenation parameters in preterm infants with respiratory distress syndrome
Abstract
The aim of the study is to study the importance of oxygenation indicators: Alveolar–arterial gradient (AaDO2) and Oxygenation Index (Oİ) in diagnosing and predicting the course of respiratory distress syndrome (RDS) in premature babies. Materials and methods of the study: 28 extremely low birth weight infants were included in the study. 12 of them (42.9%) were evaluated with Apgar scale ≤6 points, Silverman scale with 7±3 points in the first 20 minutes. RDS was confirmed in 11 (39.2%) and pneumonia in 17 (60.8%). 23 (82.1%) patients needed invasive mechanical ventilation. The number of deaths among them was 16 (57.1%). The study showed that the need for invasive mechanical ventilation in children with extremely low birth weight was associated with high values of Aa DO2 and OI, especially with FiO2 ≥ 50% in the gas-air mixture, Aa DO2 426.7 ± 225.8 mm Hg and OI 9.63±5.57, which correlated with the duration of artificial ventilation, oxygen dependence and mortality of premature infants.
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