Influence of atopic reactions on the condition of immunity at children

Abstract

98 children of primary school age (3-7 years) living in urban and rural areas were examined on cases of atopy . The parameters of immune reactivity in the period of exacerbation and during clinical remission of allergic reactions were studied (AR).
A survey of parents showed about half of urban children have atopic disease (43.3%-atopic eczema, 49% of the allergic rhinitis and 38.5% food allergosis) among rural children (0,9%; 2% and 1.9%, respectively) in the family history.
Our results correspond to the research hypotheses, linking a large number of atopic reactions in children with hereditary predisposition, the influence of the external environment, different diet, level of hygiene and lifestyle.
Changes immunofunctional parameters in urban children remaining in the period of clinical remission should be considered as an additional factor provoking AR.