SARS-CoV-2-associated venous cerebral sinus Thrombosis

Abstract

Venous thrombosis is a pathological condition in which, as a result of the formation of an intravascular thrombus, the blood flow in the tissues is abruptly interrupted or limited. A number of studies have shown that in adults, activation of the blood coagulation system against the background of a cytokine storm due to SARS-CoV-2 led to ischemic stroke and intracranial hemorrhage.An analysis of numerous studies in children with systemic inflammatory syndrome revealed an unexpectedly high incidence of ischemic and hemorrhagic cerebrovascular complications in them. Our article describes the clinical picture of parenchymal hemorrhage, as well as thrombosis of the cerebral venous sinuses in a newborn, which developed as a result of a multisystem inflammatory syndrome associated with SARS-Cov2.